Báo cáo khoa học: Cellular response to unfolded proteins in the endoplasmic reticulum of plants

Cellular Response to Unfolded Proteins in the Endoplasmic Reticulum of Plants

Author: Reiko Urade

Field: Division of Food Science and Biotechnology, Graduate School of Agriculture, Kyoto University, Japan

Document Content:
This review article discusses the unfolded protein response (UPR) in plants, a fundamental system conserved across eukaryotic cells for maintaining endoplasmic reticulum (ER) homeostasis. While the UPR is well-understood in yeast and mammals, its study in plants is a more recent development. The article summarizes recent advancements in understanding the plant UPR, focusing on its molecular mechanisms, transcriptional regulation, and the enhancement of cellular quality control systems. It highlights the activation of signaling pathways in response to ER stress, where misfolded or unfolded proteins accumulate in the ER. The review also touches upon the degradation of unfolded proteins and the potential for UPR to play a role in various cellular processes beyond stress response.

Detailed Table of Contents:

• Introduction
• Transcriptional regulation of UPR genes
• Signal transduction during the UPR
• Enhancing cellular quality control systems by the UPR
• Folding
• Degradation of unfolded proteins