Báo cáo khoa học: Quantitative Biology

Quantitative Biology Abstracts

Authors: Various

Field: Quantitative Biology

Document Content: This document contains a collection of abstracts from the field of Quantitative Biology, presented at a scientific conference. The abstracts cover a wide range of research topics, including the development of analytical platforms for small RNAs and ribonucleoprotein complexes, functional proteomic screening of lipases, activity-based imaging of lipolytic enzymes, characterization of bile as a multifunctional body fluid, studies on tellurite resistance mechanisms in bacteria, proteomic analysis of sumoylation, molecular classification of thyroid lesions, automated generation of PCR primers, analysis of protein interactions within plant signaling pathways, quantitative western blot for systems biology, modeling of cell cycle transitions, cross-talk of MAP kinase pathways, studies on transcriptional control networks, connection between cell cycle and circadian rhythm, modeling of DNA repair enzymes, dynamics of molecular machines, comparative analysis of protein-ligand interactions, kinetic analysis of enzyme mechanisms, and investigation of protein conformations and amyloid formation.

Detailed Table of Contents:

• E1-1: Development of mass spectrometry-based analytical platform for small RNAs and ribonucleoprotein complexes
• E1-2: Functional proteomic screening of lipases using click chemistry methods
• E1-3: Activity-based imaging of lipolytic enzymes in gel electrophoresis
• E1-4: Bile – a multifunctional body fluid with unexpected features
• E1-5: The role of the ter operon in tellurite resistance mechanism in E. coli
• E1-6: Proteomic analysis of sumoylation in HPV-positive human cervical carcinoma
• E1-7: Molecular classification of the follicular thyroid lesions by microarray data
• E1-8: Automated generation of PCR primers for a genomewide knock-out in Candida glabrata
• E1-9: Analysis of protein interactions within the cytokinin-signaling pathway of Arabidopsis thaliana
• E2-1: Quantitative western blot for systems biology
• E2-2: A tool for structural biology
• E2-3: Timetics vs. kinetics: on the role of temporal patterns and time-time interactions in biocatalytic systems
• E2-4: Connection between the cell cycle and the circadian rhythm in mammalian cells
• E2-5: Modeling of the G₁/S transition in yeast cell cycle
• E2-6: Cross-talk of MAP kinase pathways in Saccharomyces cerevisiae
• E2-7: Studies on the role of HAP4, MIG1 and MIG2 in transcriptional control network of Saccharomyces cerevisiae
• E2-8: Evolution and conservation of genetic interactions in C. elegans
• E2-9: Methods for highly accurate discovery of states of genetic expression and roles in systems discovery
• E3-1: The dynamics of molecular machines: Studying assembly and disassembly of complexes in vivo with fluorescence techniques
• E3-2: Dynamic analysis of complex ribonucleoprotein assembly using quantitative LC-MS methods
• E3-3: The dynamic molecular machinery of glutamate racemase
• E3-4: The ribosome
• E3-5: Identification of in vivo heat shock protein (HSP)-interacting proteins in dependence of environment
• E3-6: Cooperativity and kinetic mechanism of phosphorylated L-type pyruvate kinase
• E3-7: Multiple conformational changes in DNA repair enzymes: evidence for an induced fit mechanism
• E3-8: Study of dynamics of mammalian DNA repair machines by affinity labeling technique
• E3-9: Kinetic analysis of the interaction between rat dopamine transporter (rDAT) and its inhibitors
• E3-10: Catalytic mechanics of multidomain enzymes
• E3-11: Comparison of effect of dimethylarsinic acid and dimethyl sulfate on tubulin assembly
• E3-12: A molecular beacon sensor for the ecdysone receptor proteins
• E3-13: Allostery in PDZ domains probed by molecular dynamics and Rosetta design
• E3-14: Kinetic Capillary Electrophoresis: a Swiss Army Knife for studying dynamics of biomolecular complexes
• E4-1: Characterization of the conformations of the Amyloid-ẞ peptides using a combination of MD simulations with NMR experiments
• E4-2: Two Abl-SH3 domain peptides in amyloid formation
• E4-3: Insights into the role of odorant-binding proteins from metadynamics simulations
• E4-4: Efficiency and reliability of ribosome biogenesis in yeast
• E4-5: Force is generated by elongation of the actin filament
• E4-6: Structural and functional bioinformatic model for inhibition of human Carnitine-palmitoyltransferase 1
• E4-7: Structure and function studies of MD-ACO1 for a 1-aminocyclopropane-1-carboxylate oxidase enzyme activity
• E4-8: Evolution of the bifurcation phenotype – phylogenetic reconstruction and inverse analysis of yeast GATA networks